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Phentermine is quickly absorbed after swallowing. Peak plasma levels occur within 1 to 3 hours, varying with the degree of physical activity and the amount of food in the stomach. Absorption is usually complete by 4 to 6 hours. Sustained release preparations are available as resin-bound Ionamin, rather than soluble salts. These compounds display reduced peak blood levels compared with standard amphetamine preparations, but the total amount absorbed and the time to reach peak levels are similar.
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